I very rarely think about the possible reactions of the readers. What I think about the fic in process/planning is far more important. People either like or dislike the result, I can hardly change that (unless, of course, the issue is the style, not the content; there is no excuse for bad grammar and typos XD).
I've written for myself for so long that it's hard to imagine I would ever write what someone else wants. Sure, it could be challenging, or nice in case mine and that person's interests are the same, but... You should always write what you think is worth the shot, or what you feel like writing.